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Peptides: What are they?

By L. Johnston 3 years ago

Peptides: What Are They?

Peptides are biological materials that are made from building blocks called amino acids. Animals get most of their amino acids from the foods they eat. Different cells then assemble these amino acids into long chains called peptides or proteins. As the chains grown in length, they are able to fold back on themselves. As it turns out, certain amino acids can interact with one another when peptide chains fold. This results in the folds being locked into place, under normal physiologic conditions, which gives the peptide chain a three-dimensional structure. The length of the peptide chain as well as the order of the amino acids in it determines how the peptide folds and thus its ultimate three dimensional structure.

Receptors, special biological machines to which proteins can bind, will only accept proteins that have the right order of amino acids and the right three dimensional shape. By varying these two properties, it is possible to create proteins that have specific and very diverse functions. Research studies have shown that the peptide that binds to receptors in the heart, for instance, may not interact at all with receptors in the stomach or lungs. This allows for very specific signals to be sent from one region of the body to another, which allows for coordinated actions such as immune function, carbohydrate metabolism, and so forth.

Small Peptides

There is no formal definition for what makes a peptide “small,” but they often don’t have much in the way of three-dimensional structure. They may have a fold or two, but that is about it. These peptides rely more on their amino acid sequence than their 3-D structure for signaling. Even a small change in the order of the amino acids of a small peptide (or even the number) can make a huge difference in terms of the receptors that it can bind to. Sometimes, a change of just a single amino acid is enough to completely alter the function of a small peptide.

In the past, most of the research focus was on larger peptides and massive proteins. This was because most scientists thought that biologically active proteins were large. It was also thought that the best way to develop therapeutics was to exactly mimic existing proteins. This approach, however, isn’t entirely accurate.

New research is indicating that small peptides are not only easier to make; they can also have a wide range of biological activity. It is no longer thought that mimicking naturally occurring proteins is the best way to develop therapeutics. Science has now shifted its focus to small peptides and their potential. This shift makes sense given that small peptides have been shown to have applications ranging from antibiotics and heart medications to preventative solutions for diseases like diabetes. They have even been shown to have anti-aging effects in animal models.

The Future of Small Peptides

It is clear that the future of medicine will be rife with small peptides. They won’t be the only therapeutics available, but they will continue to make up a larger and larger percentage of the substances we use to promote health. Most importantly, small peptides can be custom-made to fight off disease and preserve health. They are less complicated to synthesize and produce and what we learn from early research trials will certainly inform us moving forward. Within a decade or two, small peptides will be as common in the medical field as antibiotics and vaccines are today.

What is a Peptide? (Part 2)

By Logan 4 years ago

A peptide is nothing more than a string of amino acids that is similar to, but not identical to, a protein. To understand what a peptide is and how it differs from a protein, it is necessary to first understand what an amino acid is.

What Are Amino Acids?

Amino acids are biologically important molecules, but not all of them are used by living organisms. In fact, the human body requires only 20 different amino acids to function (the case for almost all living things), even though nearly 500 have been identified in the universe so far. Amino acids have two specific chemical structures, called amine and carboxylic acid groups, at opposite ends. These structures endow amino acids with a common set of functions and define how they interact with one another and with other molecules.

What is a Peptide?

By Michael 6 years ago

A peptide is a chain of amino acids linked to one another by amide (peptide) bonds. A peptide bond is the covalent chemical bond formed when the carboxyl group of one amino acid reacts with the amino group of another. The word peptide is derived from the greek word πεσσειν, which means "to digest." Peptides are an essential part of nature and there are thousands of them that occur naturally in the human body and in animals, but new synthetic peptides are being discovered daily, which show a promising future for health and drug development. The benefits of peptides on health have been demonstrated in numerous research studies related to neurological function, anti-aging, muscle growth, skin wrinkles, growth hormone deficiency and so forth.

Highly Purified and Additive Free Peptides

By Michael 6 years ago

No matter what the industry, the quality of a business’s product offering is always of paramount importance to the consumer. When it comes to the purchase of peptides, it’s clear that there is no substitute for obtaining only the most pure and highest quality peptides. Lower quality peptides can be ridden with fillers like mannitol that can greatly impact your research results. Don’t sacrifice time and money for an inferior product; make sure that you only buy peptides of premium quality available from PeptideSciences.com. Our company spares no expense in ensuring that our peptides are of the highest possible purity and quality. Don’t settle for anything less than first-rate premium-quality peptides.

Our Philosophy On Peptides

By Kenneth 6 years ago

Healthy living is an essential concern to all of us, and the drive to improve our well-being is as vital as it is universal. An invaluable part of this relentless pursuit is driven by clinical research involving growth hormone peptide compounds such as Growth Hormone Releasing Hexapeptide (GHRP-6) and Ipamorelin. That's why we at PeptideSciences.com are committed to offering only the highest quality peptides for research and laboratory applications. Our company maintains a vigorous passion for investigation and discovery shared by the thousands of researchers worldwide that have made us their exclusive peptide supplier. At PeptideSciences.com we're fervently engaged in the quest to uncover the exciting possibilities presented by the utilization of peptides in future therapeutic applications, and we're dedicated to doing our utmost to provide only the best quality Sermorelin and other peptides, such as Hexarelin, to researchers striving to unlock the potential of this extraordinary peptide.

Peptide Research Article for GHRP-2, GHRP-6, Ipamorelin

By Michael 7 years ago

At Peptide Sciences, we’re always on the lookout for new studies conducted using peptides or articles written by researchers about Melanotan 2, Ipamorelin, Hexarelin or CJC-1295 in general. An almost immeasurable amount of studies have been published that demonstrate the powerful effects of GHRP-2 and GHRP-6, such as the promotion of lean muscle tissue growth as well as the stimulation of adipose (fat) tissue loss. Likewise, a great many articles have been written that bolster and clarify these study results for peptides such as Growth Hormone Releasing Peptide. However, few writers actually attempt to make the case for continued HGH peptide research on a purely philosophical level, so I was intrigued when I recently stumbled across this article. Though admittedly verbose, it offers a fresh look at the driving force behind studies involving peptides, and indeed most medical research in general. The call for continued research is one echoed by us at PeptideSciences.com as well.